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Monitoring of Tacrolimus in Oral Fluids

This is a novel, highly reproducible method for the measurement of tacrolimus in oral fluid samples. The technology uses validated liquid chromatography-tandem mass spectrometry methods (LC-MS/MS), and can potentially provide improved patient safety and allograft survival rates.

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Integrated Finite Element and Circulatory Model for Predicting Hemodynamic Effects of Left Ventricular Impairment, Resynchronization and Remodeling

This invention and the associated software provide a useful platform for modeling and simulation that assists the development and operation of a variety of medical devices pertaining to cardiovascular diseases. The computational model determines the dynamics of a left ventricle continuously over consecutive cardiac cycles by integrating finite element model of the left ventricular wall with a complex electrical analog circulatory model. It allows prediction of hemodynamic outcome of a regional left ventricular impairment.

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CPU Cache Architecture to Minimize Power Consumption

Cached data is dynamically transformed to minimize power consumption, and therefore battery life in electronic devices. This cache memory system is coupled to a main memory and a processing unit, and provides significant energy savings.

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Electrical Conductivity Enhancement of Graphene Nanoplatelet Composites Using a Non-Conductive Filler

This technology produces a massive increase in the electrical conductivity of a multilayer graphene (MLG)/polystyrene composite following the addition of nonconducting silica nanoparticles. The nonconducting filler acts as a highly effective dispersion aid, preventing the sheetlike MLG from restacking or agglomerating during the solvent casting process used to fabricate the composite. The enhanced dispersion of the MLG leads to orders of magnitude enhancement in electrical conductivity compared to samples without this filler.

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Novel Phytochemicals from Extracts of Maple Syrups and Maple Trees and Uses Thereof

The present invention describes phytochemicals present in maple syrup and maple tree extracts by butanol, ethyl acetate and methanol. Novel compounds are isolated from maple syrups, including one compound Quebecol generated in the maple syrup manufacturing process. Also described are digesting extracts of maple syrup.

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Skin Whitening Compounds Using a Gallotannin

New skin whitening gallotannin compounds are isolated from the maple tree and synthesized into more potent analogs.

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Anti-Diabetic Compounds from Tropical Fruit

This invention provides for novel related anti-diabetic compounds from Jamun seeds and pomegranate flowers which offer a variety of treatments using individual or mixtures of these anti-diabetic compounds for either a selected population group or an individual.

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Data Retrieval System that Provides Retrieval of Data to Any Point in Time

This new disk array architecture is capable of providing timely recovery to any point-in-time for user data stored in the array, referred to as TRAP (Timely Recovery Any Point) array. This new architecture has little negative impact on application performance while providing continuous data protection capability, additional security and reducing storage space requirements.

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Systems and Methods for Providing Microfluidic Devices

For licensing or sponsorship information, contact Michael Katz at mekatz@uri.edu or 401-874-4807.

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Systems and Methods for Recovering information from NAND gates Array Memory Systems

For licensing or sponsorship information, contact Michael Katz at mekatz@uri.edu or 401-874-4807.

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Systems and Methods for Sleep Apnea Detection from Breathing Sounds

For licensing or sponsorship information, contact Michael Katz at mekatz@uri.edu or 401-874-4807.

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Use of Reactive Lithium Alkoxyborates as Electrolyte Additives in Electolytes for Lithium Ion Batteries

For licensing or sponsorship information, contact Michael Katz at mekatz@uri.edu or 401-874-4807.

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Thermofluorescent Pigments for Security and Safety Applications

This invention uses polythiophene compounds to determine the genuineness of an article.

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Thin Film Ceramic Thermocouples

For licensing or sponsorship information, contact Michael Katz at mekatz@uri.edu or 401-874-4807.

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Thin Film Platinum-Palladium Thermocouples for Gas Turbine Engines

For licensing or sponsorship information, contact Michael Katz at mekatz@uri.edu or 401-874-4807.

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Systems and Methods for Providing Distributed Load Monopole Antenna Systems

This invention is a distributed-load monopole (DLM) antenna which is 70 percent smaller than conventional designs, with comparable sensitivity and increased bandwidth. The antenna uses a helix and a load coil to shrink the size of a normal quarter-wave monopole.

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Selective Surface Smoothing Using Lasers

The technology is a micro melting process to melt surface irregularities or features on a surface of a substrate. The method includes providing a laser and a control mechanism associated with the laser. The control mechanism varies the laser intensity and direction by varying and monitoring the power of the laser while simultaneously considering multiple key factors.

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Selective Delivery of molecules into cells or marking of cells in diseased tissue regions using environmentally sensitive transmembrane peptide (pHLIP related)

For licensing or sponsorship information, contact Michael Katz at mekatz@uri.edu or 401-874-4807.

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SCSI-TO-IP Cache Storage Device and Method

For licensing or sponsorship information, contact Michael Katz at mekatz@uri.edu or 401-874-4807.

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Resource Flow Computing Device Patent 3-Not Taken Path Instruction for Selectively Generating A Forwarded Result from a Previous Instruction Based on Branch Outcome

For licensing or sponsorship information, contact Michael Katz at mekatz@uri.edu or 401-874-4807.

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Processor Controlled Voltage-Current Analysis for Nerve and Muscle

For licensing or sponsorship information, contact Michael Katz at mekatz@uri.edu or 401-874-4807.

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Systems and Methods for finite element based topology optimization

For licensing or sponsorship information, contact Michael Katz at mekatz@uri.edu or 401-874-4807.

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Systems and Methods for On-Chip Power Management

For licensing or sponsorship information, contact Michael Katz at mekatz@uri.edu or 401-874-4807.

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System and Method for Branch Misprediction Prediction Using A Misdirected Branch Table Having Entry Eviction Protection

For licensing or sponsorship information, contact Michael Katz at mekatz@uri.edu or 401-874-4807.

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Systems and Methods for Distance Estimation between Electronic Devices

For licensing or sponsorship information, contact Michael Katz at mekatz@uri.edu or 401-874-4807.

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System and Method For Maintaining Redundant Storages Coherent Using Sliding Windows of Eager Execution Transactions

For licensing or sponsorship information, contact Michael Katz at mekatz@uri.edu or 401-874-4807.

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System and Method For Cache Replacement

For licensing or sponsorship information, contact Michael Katz at mekatz@uri.edu or 401-874-4807.

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Polymer-Bound Phosphitylating Reagents for the Synthesis of Organophosphorous Compounds

For licensing or sponsorship information, contact Michael Katz at mekatz@uri.edu or 401-874-4807.

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Method for Improved Electrical Conductivity of Graphene Nanoplatelet Composites

For licensing or sponsorship information, contact Michael Katz at mekatz@uri.edu or 401-874-4807.

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Method for Acoustic Measurements of Physiological Signals

For licensing or sponsorship information, contact Michael Katz at mekatz@uri.edu or 401-874-4807.

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Method and Apparatus for Measuring Electrical Properties

For licensing or sponsorship information, contact Michael Katz at mekatz@uri.edu or 401-874-4807.

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Male and Female Sterility Lines Used to Make Hybrids in Genetically Modified Plants

For licensing or sponsorship information, contact Michael Katz at mekatz@uri.edu or 401-874-4807.

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Methods of Facilitating the Bioconversion of Crude Biodiesel-Derived Glycerol by Microorganisms

For licensing or sponsorship information, contact Michael Katz at mekatz@uri.edu or 401-874-4807.

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Modified Freeze Fracture Direct Imaging Apparatus and Technique

For licensing or sponsorship information, contact Michael Katz at mekatz@uri.edu or 401-874-4807.

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Non-Detonable Explosive-Simulant Source

For licensing or sponsorship information, contact Michael Katz at mekatz@uri.edu or 401-874-4807.

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Non-Invasive Automated Electrical Control Systems and Methods for Monitoring Animal Conditions

For licensing or sponsorship information, contact Michael Katz at mekatz@uri.edu or 401-874-4807.

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Novel Cathode Film Forming Additives for Lithium Ion Batteries with High Voltage Cathodes

For licensing or sponsorship information, contact Michael Katz at mekatz@uri.edu or 401-874-4807.

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Novel Process for Electroless Plating of Gold on Surface

For licensing or sponsorship information, contact Michael Katz at mekatz@uri.edu or 401-874-4807.

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Novel Regulatory T Cell Epitope and Hepatitis C Virus Homolog

For licensing or sponsorship information, contact Michael Katz at mekatz@uri.edu or 401-874-4807.

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Enhanced Microfluidic Valve for Media Diagnostics

For licensing or sponsorship information, contact Michael Katz at mekatz@uri.edu or 401-874-4807.

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Electrolyte for Lithium Ion Batteries

Discovery of a new lithium salt, lithium tetrafluorooxalatophosphate (LiPF4(C2O4), LiF4OP), has been designed as a new compound and a synthetic method for the preparation of this new lithium salt is developed.

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Electrochemical Cells (Original Title: Electrolyte Additives to Improve Performance of High Voltage Spinel)

For licensing or sponsorship information, contact Michael Katz at mekatz@uri.edu or 401-874-4807.

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Delivery of DNA Vaccines into Fish by Immersion

A method of immunizing fish against bacterial and viral infection by immersing the fish in a solution of dead or attenuated, whole-celled recombinant bacteria. The recombinant bacteria has a eukaryotic expression vector (plasmid) incorporated with DNA of interest encoding at least one protein antigen for each of the pathogens. The protein antigen is produced by the fish.

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Environmentally Sensitive Compositions (pHLIP related)

For licensing or sponsorship information, contact Michael Katz at mekatz@uri.edu or 401-874-4807.

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FiberID – Molecular-Level Secret for Identification of Things

For licensing or sponsorship information, contact Michael Katz at mekatz@uri.edu or 401-874-4807.

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Low TCR Nanocomposite Strain Gages

For licensing or sponsorship information, contact Michael Katz at mekatz@uri.edu or 401-874-4807.

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Liposome Compositions and Methods of Use Thereof (pHLIP related)

For licensing or sponsorship information, contact Michael Katz at mekatz@uri.edu or 401-874-4807.

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Integrated Finite Element and Circulatory Model for Predicting Hemodynamic Effects of Left Ventricular Impairment, Resynchronization and Remodeling

For licensing or sponsorship information, contact Michael Katz at mekatz@uri.edu or 401-874-4807.

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Highly Ordered TiO2 and Pt/TiO2 Nanocomposites for Advanced Catalytic Applications

For licensing or sponsorship information, contact Michael Katz at mekatz@uri.edu or 401-874-4807.

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Particle Templated Flexible Composites with Tunable Properties

A flexible conductive composite that has been co-optimized for both electrical and mechanical properties has been created.

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Fixed Angle Rotary Shear: A New Method for Tailoring Composite Materials

The Fixed-Angle Rotary Shear Technique is a simple, inexpensive method that can be used to distribute conductive filler materials into specially constructed architectures throughout polymers on either the micro/macro scale without the use of organic solvents.

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Anti-Inflammatory and Quorum Sensing Inhibition compounds and Methods of Making and Using Them

For licensing or sponsorship information, contact Michael Katz at mekatz@uri.edu or 401-874-4807.

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Apparatus for Neuron Emulation and Testing

For licensing or sponsorship information, contact Michael Katz at mekatz@uri.edu or 401-874-4807.

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Biomedical Electrode for Detecting Localized Electrical Signals and Providing Electrical Stimulation (Patent 1) Patent 2 – Biomedical Electrode System and Method for Detecting

For licensing or sponsorship information, contact Michael Katz at mekatz@uri.edu or 401-874-4807.

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Biomedical Sensors Usable on Unprepared Contact Surfaces

For licensing or sponsorship information, contact Michael Katz at mekatz@uri.edu or 401-874-4807.

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Bisubstrate Inhibitors of Protein Tyrosine Kinasis as Therapeutic Agents

For licensing or sponsorship information, contact Michael Katz at mekatz@uri.edu or 401-874-4807.

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Cache architecture for a processing unit providing reduced power consumption in cache operation

For licensing or sponsorship information, contact Michael Katz at mekatz@uri.edu or 401-874-4807.

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Composite used for Thermal Spray Instrumentation and Method for Making the Same

A superalloy article of a substrate, bond coat (cobalt, nickel or mixtures thereof) applied onto the substrate, and a ceramic top coat applied over the bond coat. The bond coat is exposed to a 1600-1800 degrees F after its application onto the substrate.

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An Improved Method for the Detection of Peroxides Using Nanocomposite Catalysts

For licensing or sponsorship information, contact Michael Katz at mekatz@uri.edu or 401-874-4807.

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Aerobic Oxidative Coupling for the Formation of Biaryls

A method of catalytic oxidative coupling for the formation of hetero-coupled biaryls. The method includes placing a solvent, an arene compound, and a catalyst in a reactor having a oxidant atmosphere such that hetero-coupled biaryls are formed.

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Nanofibrous Materials as Drug, Protein or Genetic Release Vehicles

For licensing or sponsorship information, contact Michael Katz at mekatz@uri.edu or 401-874-4807.

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Electrospinning Process for Making a Textile Suitable for Use as a Medical Article

For licensing or sponsorship information, contact Michael Katz at mekatz@uri.edu or 401-874-4807.

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A Chemical Sensor Based on an Array of Fluorophores with Enhanced Emission

For licensing or sponsorship information, contact Michael Katz at mekatz@uri.edu or 401-874-4807.

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A Method for the Production of Non-Transgenic Wide Cross Hybrids Using Transgenic Intermediates

For licensing or sponsorship information, contact Michael Katz at mekatz@uri.edu or 401-874-4807.

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A Multiferro-Heterostructure Composition Having Tunable Magnetic Coupling at Room Temperature

The invention provides a ferromagnetic/ferroelectric heterostructure thin film that exhibits tunable magneto-electric coupling with room temperature functionality.

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A New Paper-Based Platform Technology for Point-of-Care Diagnostics

The recently invented Paper Based Microfluidic Valve (PBMV) technology constitutes a platform technology that allows for sequential manipulation of fluids on paper without operator intervention. Complex multi-reagent quantitative assays not possible with conventional strip tests can now be performed.

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High Temperature Strain Gages

A ceramic strain gage based on reactively sputtered indium-tin-oxide (ITO) thin films is used to monitor the structural integrity of components employed in aerospace propulsion systems operating at temperatures in excess of 1500° C with little signal draft. Preferred semi-conductor is ITO and preferred metal is platinum.

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A Method for Obtaining Highly Conductive Graphene-Based Composites

This Electrostatic Dispersion technique is a simple, inexpensive method that can be used to disperse conductive particles (i.e. Graphene, Carbon Nanotubes, Graphite, Carbon black particles, Mineral flakes, etc.) in a highly organized manner within non-conducting polymer materials.

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